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Synthesis and Processing of Poly(pro-drug) Materials for Extended Drug Release and Uses Thereof
RPI ID:
2019-013-401 / 2019-013-601
Innovation Summary:
A poly(pro‑drug) platform constructs biodegradable polymers in which the therapeutic molecule itself—such as estradiol, curcumin, or fingolimod—forms the repeating backbone, linked by cleavable ester, carbonate, or urethane groups and separated by hydrocarbyl or PEG‑based spacers....
Published: 3/10/2026
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Updated: 3/10/2026
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Inventor(s): Edmund Palermo, Anthony D'Amato, Ryan Gilbert, Samuel Ellman
Keywords(s): Biomaterial, Drug Delivery, hormone, pro-drug
Category(s): Biotechnology and the Life Sciences
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Electrospun fibers with altered drug release profiles resulting from changes in polymer crystallinity
RPI ID: 2016-017-401 and 2016-017-601
Innovation Summary:
This invention presents a drug delivery platform based on electrospun polymeric fibers that enable controlled, localized, and sustained release of therapeutic agents. The system uses biodegradable polymers to encapsulate drugs within nanofibers, allowing for precise tuning of release kinetics...
Published: 7/21/2025
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Updated: 7/7/2025
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Inventor(s): Anthony D'Amato, Andrew Fiumara, Paul Troiano, Jesus Cardenas, Ryan Gilbert, Nicholas Schaub
Keywords(s): Biomedical Engineering, Delivery, Drug Delivery, Materials, Polymers
Category(s): Biotechnology and the Life Sciences
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