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Ligand design method for affinity capture of mRNA in solution and on a surface and ligands discovered thereof
RPI ID:
2022-061-601
Innovation Summary:
This technology describes ligands and associated methods for affinity capture of mRNA molecules in solution. The ligands are designed to bind selectively to mRNA surfaces, enabling efficient isolation and purification. The system supports scalable mRNA processing for therapeutic and research applications. It...
Published: 3/10/2026
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Updated: 3/10/2026
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Inventor(s): Todd Przybycien, Mirco Sorci, Thomas Neuman, Riddhi Banik, Georges Belfort
Keywords(s): mRNA, Purification, Vaccine
Category(s): Biotechnology and the Life Sciences
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Directed evolution for Membranes Development in 3 Dimensions
RPI ID: 2021-036-201
Innovation Summary:
Directed evolution techniques are applied to develop three-dimensional membrane structures with enhanced permeability and selectivity. The system uses iterative mutation and selection cycles to optimize membrane protein configurations. It supports applications in filtration, sensing, and biointerfaces. The method...
Published: 3/10/2026
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Updated: 3/10/2026
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Inventor(s): Joel Plawsky, Mirco Sorci, Chenyu Guan, Georges Belfort
Keywords(s): bioprocessing, food processing, membrane microfiltration, Separations
Category(s): Biotechnology and the Life Sciences
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An assay to evaluate the filtration of suspended particles in existing and hypothetical micro-porous membranes
RPI ID: 2019-059-401Innovation Summary:This invention introduces a novel assay designed to evaluate the filtration efficiency of microporous membranes in removing suspended particles. The method leverages a controlled particle suspension and quantifies membrane performance through precise measurement of particle retention and flow characteristics. It...
Published: 7/21/2025
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Updated: 7/3/2025
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Inventor(s): Georges Belfort, Joel Plawsky, Corey Woodcock, Mirco Sorci, Dustin Andersen
Keywords(s): Assay, computational fluid mechanics, intermolecular forces, pore imaging, relative species transport rates, Selectivity
Category(s): Biotechnology and the Life Sciences
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Combined Plasma-ARGET ATRP Method and Materials For Modifying Poly(ether sulfone) Surface
RPI ID: 2017-007-401Innovation Summary:This invention presents a method for modifying polymeric surfaces using atmospheric pressure plasma followed by atom transfer radical polymerization (ATRP). The process activates the surface, attaches an initiator, and then grows polymer chains to tailor surface properties. It enables precise control over surface...
Published: 7/21/2025
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Updated: 7/3/2025
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Inventor(s): Georges Belfort, Istvan Kocsis, Mirco Sorci, Alexander Lee, John Keating
Keywords(s): Advanced Materials, ARGET ATRP, Biological\Chem Separation\Purification Tech, Biotechnology, Chemistry, coatings/adhesives/composites, Consumer product, Desalination, Design, Devices, Devices/instruments, Energy, Energy efficiency, Environment, Films, Human healthcare, Material science, membrane systems, Membrane Technology, Membranes, Nanotechnology, Nanotechnology (nanocomposites), Organics Recovery, pharmaceutical, plasma, plastics, Polymer Brush, polymer composite, polymer/epoxy resins, polymerization, Polymers, Proteins, research reagents/tools, Sensors, Surface modification, Technology
Category(s): Nanotechnology and Advanced Materials
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