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Peptide ligands for affinity capture of mRNA and methods of discovery thereof
RPI ID:
2022-060-301
Innovation Summary:
This technology describes peptide ligands engineered for the affinity capture of nucleic acids, including DNA and RNA, in solution. These ligands are designed to bind selectively to nucleic acid targets, enabling efficient isolation and purification. The method includes synthesis and screening of peptide sequences...
Published: 3/10/2026
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Updated: 3/10/2026
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Inventor(s): Pankaj Karande, Mengyang Hu, Georges Belfort
Keywords(s): mRNA, Peptides, Purification, Vaccine
Category(s): Biotechnology and the Life Sciences
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Ligand design method for affinity capture of mRNA in solution and on a surface and ligands discovered thereof
RPI ID:
2022-061-601
Innovation Summary:
This technology describes ligands and associated methods for affinity capture of mRNA molecules in solution. The ligands are designed to bind selectively to mRNA surfaces, enabling efficient isolation and purification. The system supports scalable mRNA processing for therapeutic and research applications. It...
Published: 3/10/2026
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Updated: 3/10/2026
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Inventor(s): Todd Przybycien, Mirco Sorci, Thomas Neuman, Riddhi Banik, Georges Belfort
Keywords(s): mRNA, Purification, Vaccine
Category(s): Biotechnology and the Life Sciences
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Hydrophobic Brush Membranes for Filtration Based on Solution-Diffusion Mechanism with Applications to Pervaporation (PV) & Reverse Osmosis (RO)
RPI ID: 2015-029-401, 2015-029-601, 2015-029-602, 2015-029-603Innovation Summary:This invention describes a synthetic membrane system designed to purify water and isolate volatile organic compounds. The membrane includes a hydrophobic polymer layer supported by a polymeric substrate, allowing for selective pervaporation or reverse osmosis. The technology...
Published: 7/21/2025
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Updated: 7/3/2025
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Inventor(s): Georges Belfort, Joseph Grimaldi, Joseph Imbrogno, James Kilduff
Keywords(s): Chemical Engineering, Energy, Energy Management, Material Sciences\Engineering, Materials, Monomers, Polymers, Purification, Small Molecule
Category(s): Biotechnology and the Life Sciences
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