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Cross-linkable matrix-free nanocomposites with tunable optoelectronic functionalities and the methods for their macro-, micro- or nano-structures construction
RPI ID:
2014-054-402
Innovation Summary:
Introduces solid-state, matrix-free polymer nanocomposites built entirely from polymer-brush–grafted nanoparticles without a separate bulk polymer matrix. A multimodal (bi- or polydisperse) brush design places dense short chains near the nanoparticle surface for strong steric shielding while...
Published: 3/10/2026
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Updated: 3/10/2026
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Inventor(s): Charles Goodwin, Robert, Jr. Karlicek, Ying Li, Linda Schadler Feist, CHAITANYA ULLAL
Keywords(s): Amyloid Fibrils, Amyloidosis, Biomedical Engineering, Diagnostics, Measurement, Medical Device\Diagnostic Systems, Proteins, SEM1/SEM2, serum amyloid A, SEVI, Staining
Category(s): Biotechnology and the Life Sciences
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Rapid Filtration Methods for Dual-energy X-ray CT
RPI ID: 2016-056-401, 2016-056-601, 2016-056-602, 2016-056-603Innovation Summary:This portfolio features a suite of advanced filtration technologies developed to enhance the performance of dual-energy X-ray computed tomography (DECT) systems. These innovations address key limitations in spectral separation, motion artifact reduction, and computational...
Published: 7/21/2025
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Updated: 7/7/2025
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Inventor(s): Wenxiang Cong, Yan Xi, Ge Wang
Keywords(s): Biomedical Engineering, computed tomography (CT), Diagnosis, Dual-energy X-ray CT, dual-layer x-ray detection, dual-source scanning, Imaging, kVp-switching, Measurement, Safety
Category(s): Biotechnology and the Life Sciences
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Energy-sensitive Multi-contrast Cost-effective CT (E=MC^2) System
RPI ID: 2016-047-401Innovation Summary:This invention presents a method for improving CT image reconstruction using a multi-contrast cost function. The system incorporates energy-sensitive data to enhance image quality and reduce artifacts. It is particularly effective in dual-energy and spectral CT imaging, where multiple contrast levels must be balanced....
Published: 7/21/2025
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Updated: 7/3/2025
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Inventor(s): Wenxiang Cong, Ge Wang
Keywords(s): attenuation imaging, Biomedical Engineering, Diagnosis, grating imaging, Imaging, Measurement, phase-contrast imaging, Proteomics, x-ray dark-field imaging
Category(s): Biotechnology and the Life Sciences
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Cell Chirality Based Three Dimensional Microassay for Disease Detection and Drug Screening
RPI ID: 2015-045-201Innovation Summary:This invention describes a 3D method for measuring cellular chirality, which is critical for early detection of diseases like cancer and developmental disorders. Cells are cultured in a multi-layered 3D substrate that mimics tissue environments more accurately than traditional 2D cultures. The system determines...
Published: 7/21/2025
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Updated: 7/3/2025
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Inventor(s): Amanda Chin, Qun (Leo) Wan
Keywords(s): Assay, Biomaterials\Tissue Engineering, Biomedical Engineering, Chirality, HTS, Imaging, Measurement, Morphogenesis, Stopper
Category(s): Biotechnology and the Life Sciences
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