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Patient-Specific Organ Dose Quantification and Optimization for CT
RPI ID: 2020-032-401
Innovation Summary:
A computational method enables quantification of organ-specific radiation dose during CT imaging and uses inverse optimization to adjust scan parameters accordingly. The system incorporates patient-specific anatomical models and dose-response data to guide personalized imaging protocols. It supports real-time...
Published: 3/10/2026
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Updated: 3/10/2026
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Inventor(s): Pingkun Yan, Birsen Yazici, Xie Xu
Keywords(s): AI workflow, Artificial Intelligence Radiology, Clinical Imaging, computed tomography (CT), CT dosimetry, CT Scanner, deep learning, Dosimetry, Imaging, medical imaging, Nuclear Medicine, Personalized Medicine, Radiology, X-Rays
Category(s): Biotechnology and the Life Sciences
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Multipurpose Micro Diffractive- Imaging Magnetooptical System
RPI ID: 2020-019-401
Innovation Summary:
A magneto-optical imaging system integrates diffractive optics to enhance spatial resolution and material-specific contrast. The system uses magnetic field modulation and diffractive lensing to visualize magnetic domains and anisotropic structures. It supports micro- and nanoscale imaging and is compatible with...
Published: 3/10/2026
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Updated: 3/10/2026
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Inventor(s): Edwin Fohtung
Keywords(s): diffractive, Imaging, laser magnetometry, magnetooptical
Category(s): Computational Science and Engineering
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Rapid Filtration Methods for Dual-energy X-ray CT
RPI ID: 2016-056-401, 2016-056-601, 2016-056-602, 2016-056-603Innovation Summary:This portfolio features a suite of advanced filtration technologies developed to enhance the performance of dual-energy X-ray computed tomography (DECT) systems. These innovations address key limitations in spectral separation, motion artifact reduction, and computational...
Published: 7/21/2025
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Updated: 7/7/2025
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Inventor(s): Wenxiang Cong, Yan Xi, Ge Wang
Keywords(s): Biomedical Engineering, computed tomography (CT), Diagnosis, Dual-energy X-ray CT, dual-layer x-ray detection, dual-source scanning, Imaging, kVp-switching, Measurement, Safety
Category(s): Biotechnology and the Life Sciences
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Energy-sensitive Multi-contrast Cost-effective CT (E=MC^2) System
RPI ID: 2016-047-401Innovation Summary:This invention presents a method for improving CT image reconstruction using a multi-contrast cost function. The system incorporates energy-sensitive data to enhance image quality and reduce artifacts. It is particularly effective in dual-energy and spectral CT imaging, where multiple contrast levels must be balanced....
Published: 7/21/2025
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Updated: 7/3/2025
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Inventor(s): Wenxiang Cong, Ge Wang
Keywords(s): attenuation imaging, Biomedical Engineering, Diagnosis, grating imaging, Imaging, Measurement, phase-contrast imaging, Proteomics, x-ray dark-field imaging
Category(s): Biotechnology and the Life Sciences
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Simultaneous Interior MRI and X-ray Imaging System (MRX)
RPI ID: 2016-022-601 and 2016-022-401
Innovation Summary:
This invention presents a portable hybrid imaging system that combines magnetic resonance imaging (MRI) and X-ray modalities in a single device. The MRX system enables simultaneous acquisition of structural and soft tissue data, improving diagnostic precision. It uses compact electromagnets...
Published: 7/21/2025
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Updated: 7/3/2025
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Inventor(s): Lars Gjesteby, Ge Wang
Keywords(s): Biomedical Engineering, Diagnosis, Imaging, Interior Tomography
Category(s): Biotechnology and the Life Sciences
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Combination of an X-ray Tube and a G0 Grating with Electron Beam Scanning
RPI ID: 2016-006-401Innovation Summary:This invention presents a hybrid X-ray tube system that uses electron beam manipulation to replace the need for traditional source gratings. Instead of relying on mechanical source grating structures, the system modulates the X-ray output via controlled steering of the electron beam. The dynamic beam pattern generates...
Published: 7/21/2025
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Updated: 7/3/2025
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Inventor(s): Wenxiang Cong, Ge Wang
Keywords(s): Biomedical Engineering, Electrical Engineering, image reconstruction, Imaging, Molecular Modeling, x-ray dark-field imaging, X-ray grating imaging, x-ray phase imaging
Category(s): Biotechnology and the Life Sciences
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Cell Chirality Based Three Dimensional Microassay for Disease Detection and Drug Screening
RPI ID: 2015-045-201Innovation Summary:This invention describes a 3D method for measuring cellular chirality, which is critical for early detection of diseases like cancer and developmental disorders. Cells are cultured in a multi-layered 3D substrate that mimics tissue environments more accurately than traditional 2D cultures. The system determines...
Published: 7/21/2025
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Updated: 7/3/2025
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Inventor(s): Amanda Chin, Qun (Leo) Wan
Keywords(s): Assay, Biomaterials\Tissue Engineering, Biomedical Engineering, Chirality, HTS, Imaging, Measurement, Morphogenesis, Stopper
Category(s): Biotechnology and the Life Sciences
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CT metal artifact reduction (MAR) using high energy x-rays
RPI ID: 2015-022-201Innovation Summary:This technology provides a computational imaging solution for reducing metal artifacts in CT scans using dual-energy datasets. It captures X-ray projection data at two different energy levels and uses a pseudo-dataset to adjust for variations in attenuation caused by metal. The method identifies metal trace regions...
Published: 7/21/2025
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Updated: 7/3/2025
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Inventor(s): Bruno De Man, Yannon Jin, Ge Wang, Yan Xi
Keywords(s): Biomedical Engineering, Imaging
Category(s): Biotechnology and the Life Sciences
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