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A Method for Generating Functional Surface Coatings and Modifications via Self-Assembly of Silk Fibroin and Silk Fibroin-Like Macromolecules
RPI ID:
2019-087-401
Innovation Summary:
A non-covalent, bottom-up coating method enables the formation of silk fibroin-based layers on chemically inert and geometrically complex surfaces. The process uses kosmotropic agents to facilitate smooth, homogeneous coatings that are tunable in thickness and free of inhomogeneities. These coatings can incorporate...
Published: 4/9/2026
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Updated: 3/10/2026
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Inventor(s): Runye Zha, Tanner Fink, Caleb Wigham
Keywords(s): antifouling coatings, bioinert, Biomaterial, biomedical coatings, Implant, implant surface, protein structure, Self Assembly, silk, spidroin, Surface modification, surface treatment, thin film coatings, universal coating
Category(s): Biotechnology and the Life Sciences
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Implantable Multilayer 3D Scaffold Consisting of Highly Aligned Electrospun Fibers for Neuronal Regeneration Applications
RPI ID: 2016-014-401, 2016-014-601Innovation Summary:This invention introduces a 3D scaffold composed of curved, highly aligned electrospun fibers designed to promote neural regeneration. The scaffold mimics natural guidance structures found in peripheral nerve grafts, using polymer fibers arranged in S-shaped or C-shaped conduits. It may incorporate...
Published: 7/21/2025
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Updated: 7/7/2025
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Inventor(s): Ryan Gilbert, Jared Cregg, Bing Wang, Michael Mullins, Martin Oudega, Andres Hurtado
Keywords(s): biocompatible, Biomedical Engineering, Electrospinning, Electrospun Fibers, Implant, Material science, Nerve Regeneration, PLLA, Polymers, scaffold, Spinal Cord Injury
Category(s): Biotechnology and the Life Sciences
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