covid19 Results | Available Intellectual Property | Rensselaer Polytechnic Institute

Search Results - covid19

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Nasal spray using PPS and MPS for COVID-19 prevention and treatment
RPI ID: 2021-049-201 Innovation Summary: A nasal spray formulation combines pentosan polysulfate and mucopolysaccharide polysulfate to prevent and treat COVID-19. The compounds act as viral entry inhibitors by blocking spike protein binding to host cells. The spray is designed for prophylactic and therapeutic use, with potential for broad-spectrum...
Published: 3/10/2026   |   Updated: 3/10/2026   |   Inventor(s): Fuming Zhang, Jawed Fareed, Walter Jeske, Robert Linhardt
Keywords(s): antiviral drug, COVID19, Heparin, mucopolysachharide polysulfate, Nasal spray, Pentosan polysulfate, prevention
Category(s): Biotechnology and the Life Sciences
Use of HCV NS3/4A Protease Inhibitors as Therapeutics for COVID-19
RPI ID: 2021-001-401 Innovation Summary: A therapeutic composition combines multiple protein inhibitors to target SARS-CoV-2 replication pathways. The method leverages synergistic interactions between inhibitors to enhance antiviral efficacy. It includes formulations for systemic and localized delivery, and supports adaptation to emerging variants....
Published: 3/10/2026   |   Updated: 3/10/2026   |   Inventor(s): Khushboo Bafna, Robert Krug, Aldolfo Garcia-Sastre, Kris White, Gaetano Montelione
Keywords(s): COVID19, COVID-19 antivirals, Hepatitis C viral protease inhibitors, Repurposed Drugs
Category(s): Biotechnology and the Life Sciences