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A method for designing active antimicrobial peptides (AMPs) specific for a given bacterial target and three highly active synthetic AMPs designed using this method against Mycobacterium tuberculosis
RPI ID: 2014-043-601Innovation Summary:This invention introduces a set of novel anti-microbial peptides effective against M. tuberculosis and streptococcus species. The peptides were developed using a computational design strategy to enhance biological activity and specificity while minimizing toxicity to human cells. The design methodology allows researchers...
Published: 7/21/2025   |   Updated: 7/3/2025   |   Inventor(s): Georges Belfort, Pankaj Karande, Zachary Kloos, Jun Kwak, Kathleen McDonough, Brian Murray, Carl Pearson
Keywords(s):  
Category(s): Biotechnology and the Life Sciences