RPI ID: 2015-027-201

Innovation Summary:
This invention describes a phase-contrast imaging system using X-rays and a dual-grating setup to visualize soft tissues and materials with weak attenuation. It includes a quasi-periodic phase grating and an analyzer grating to produce high-contrast images of subtle structural features. Second-order diffraction models and phase retrieval algorithms enhance image reconstruction from limited or scattered signals. The system enables dark-field imaging and edge detection that are not possible with standard X-ray absorption techniques. Its ability to resolve internal features in soft biological tissues, polymers, and composites makes it highly valuable for non-invasive diagnostics and material characterization.

Challenges / Opportunities:
Conventional X-ray systems cannot detect low-contrast features, limiting their effectiveness in early-stage disease detection or non-destructive testing. This technology fills that gap by enhancing contrast without increasing radiation exposure. It offers new capabilities in mammography, lung imaging, and materials research. Opportunities include developing compact phase-contrast imaging systems for clinics and labs.

Key Benefits / Advantages:
✔ Improved soft tissue visualization
✔ Enables dark-field and edge imaging
✔ Compatible with lower X-ray doses

Applications:
• Biomedical imaging (e.g., breast, lung)
• Non-destructive testing in manufacturing
• Soft material and polymer analysis

Keywords:
#phasecontrast #xrayimaging #darkfield #softtissueimaging

Intellectual Property:
US Issued Patent 9,801,600 B2